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Use this document to complete Part 2 of the Module 2 Assessment, Evidence-Based Project, Part 1 An Introduction to Clinical Inquiry and Part 2 Research Methodologies

Full citation of selected articleArticle 1Article 2Article 3Article 4DENT, D. M. PANIERI, E.

Screening for breast

cancer

finding a place between

common

sense and the evidence

base. South

African Medical

Journal

Suid-Afrikaanse

Tydskrif Vir Geneeskunde,

s. l., v. 94, n. 5,

p. 354355, 2004.

Disponvel em

directtrueAuthTypeipdbmdcAN

15211953siteehost-livescopesite.

Acesso em 1 dez. 2019

Mandrik, O., Ekwunife, O. I., Meheus, F.,

Severens, J. L. H.,

Lhachimi, S., Uyl-de Groot, C. A.,

Murillo, R. (2019).

Systematic

reviews as

a lens of evidence

Determinants

cost-effectiveness of

breast cancer

screening.

Cancer Medicine.Glasziou, P., Houssami,

N. (2011).

The evidence base

for breast cancer

screening.

Preventive

Medicine, 53(3),

100102. https//doi-org.ezproxy1.apus.

edu/10.1016/j.

ypmed.2011.05.011Himes, D. O. P. (Assistant P. P.,

Zaro, M. L. M. (Family N. P.,

Williams, M. P. (Professor), Freeborn,

D. P. (Retired P. P.,

Eggett, D. L. P.

(Professor), Kinney, A. Y. P.

(Professor). (2019).

Breast cancer risk assessment

Evaluation of screening

tools for genetics referral.

Journal of the American

Association of Nurse Practitioners

, 31(10), 56

2572.Why you chose this article and/or how it relates to the clinical issue of interest (include a brief explanation of the ethics of research related to your clinical issue of interest)

Breast cancer is both the most common and deadliest cancer among women. Also, so that every woman, whatever her age, can learn about this disease and decide, alone or with a health professional actions she can undertake to prevent and detect. DENT, D. M. PANIERI, E article deals with the gap between common sense and evidence-based practice.

Glasziou, P., Houssami, N. (2011) stated that women between the ages of 50 and 74 will be able to learn more about breast cancer screening every two years, its benefits and limitations. Some authors refer to the factors of an unfavorable prognosis and a 4-fold increase in the risk of breast cancer in women who underwent surgery for fibroadenoma, but a different pathogenetic interpretation is possible here. Ovarian removal, on the contrary, significantly reduces the likelihood of breast cancer. An analysis of randomized controlled trials has shown that mammogram screening of women 50-69 years of age reduces mortality from breast cancer by 20-25. A meta-analysis of seven randomized trials involving 500 thousand women showed a 25 reduction in mortality in the experimental group. Among women who actually took part in the screening, mortality decreased by 30-35. In the United States, screening among women 40-69 years of age has led to the fact that in 80, a tumor of less than 2 cm is diagnosed.Ultrasound is not used for screening . This method may be additional to clarify the diagnosis. In the United States and Europe, the role of NMR is increasing in breast cancer screening. NMR sensitivity is higher than mammography, specificity is lower. The high cost and lack of standardized criteria in interpreting the detected changes are significant drawbacks. Mandrik, O., Ekwunife, O. I., Meheus, F., Severens, J. L. H., Lhachimi, S., Uyl-de Groot, C. A., Murillo, R. (2019) pointed out in their research the most cost-effective ways of screening. Systematic reviews are widely accepted as a tool to increase the flow of scientific information.The patient underwent a genetic examination, according to the results of which a mutation of the BRCA1 gene was identified, which determines the susceptibility to breast and ovarian cancer. The woman decided against the use of organ-preserving treatment. She underwent a robot-assisted total laparoscopic hysterectomy and bilateral salpingoophorectomy, as well as a skin and co-preserving bilateral mastectomy with breast reconstruction. Thus, interventions in this patient significantly reduced the risk of developing breast and ovarian cancer.

Brief description of the aims of the research of each peer-reviewed articleThe United States Preventative Services Task Force (USPSTF) recommends breast cancer risk-screening tools to help primary care providers determine which unaffected patients to refer to genetic specialists. The aim of this article is to provide awareness of available screening tools and their efficiency.The history of breast cancer screening is littered with controversy. The essence of the method boils down to the fact that all women aged 50 to 70 years are recommended a regular - 1 time in 2 years - mammogram examination. It is women of this age that make up the main risk group for breast cancer.Systematic reviews help practitioners keep up with the latest medical literature by summarizing a large amount of evidence-based data and explaining the reasons for the discrepancy between the results of various studies. The systematic review uses scientific approaches that limit the possibility of systematic errors in the selection, critical assessment and generalization of all studies on a specific clinical problem. Meta-analysis is a type of systematic review in which statistical methods are used to combine and summarize the results of several original studies. Since the process of preparing a review in itself (like any other scientific research) is subject to systematic errors, a review is valuable only when it sets out in detail the methods for its preparation.The aim of this research is to find the link between genetics and prevalence of cancer occurrence. What factors can cause mutations in genes It is well known that such factors that are widely represented in the environment can be various types of radiation (ultraviolet, ionizing), mutagenic and carcinogenic chemicals (some polycyclic aromatic hydrocarbons, arsenic, chromium, nickel, etc.), some viruses.

Brief description of the research methodology used Be sure to identify if the methodology used was qualitative, quantitative, or a mixed-methods approach. Be specific.

Qualitative research design used in this study.

Systematic Reviews method used in this study

mixed-methods approach used in this study

Qualitative research design used in this study.A brief description of the strengths of each of the research methodologies used, including reliability and validity of how the methodology was applied in each of the peer-reviewed articles you selected.

Qualitative research methods are scientific methods of data analysis used in social science (eg, sociology, management, ethnography).

They allow to acquire a deep knowledge of a social phenomenon thanks to the analysis of texts (and words, rather than numbers)Mixed systematic reviews are literature reviews that use a systematic approach to combine quantitative, qualitative, and mixed studies. Uses an explicit, transparent and reproducible approachMixed systematic reviews are literature reviews that use a systematic approach to combine quantitative, qualitative, and mixed studies. Uses an explicit, transparent and reproducible approachQualitative research methods are scientific methods of data analysis used in social science (eg, sociology, management, ethnography).

They allow to acquire a deep knowledge of a social phenomenon thanks to the analysis of texts (and words, rather than numbers)General Notes/Comments

2018 Laureate Education Inc. PAGE MERGEFORMAT 2

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