FAMILY HEALTH RISK

Family Health Risk

Name

Institution

Summary

This assignment is concerned with the explanation of the “family” as the potential carrier of certain disease for individual through genetic expressions. Selected individual is C (female, 3 years) suffering from Cat’s eye reflex as her right eye has huge red spot in place of white pupil. Generation III will define her along with her siblings (2 brothers, 5yr and 7 yrs old), generation II will encapsulate her mother and father whereas generation I will encompass her maternal and paternal grandparents. In the end, some nursing interventions will be defined in this regard.

Generation I

Table 1

Paternal Grand Parents Genetic History

No.

History

Paternal Grand Father

(60 years, alive)

Paternal Grand Mother (58 years, alive)

1

Health History

Illness: Hypertension

Gynecological History: Normal

Health maintenance: Active

Illness: Alzheimer’s Disease

Gynecological History: Normal birth

Health maintenance: Active

2

Reproductive History

Sexual maturity: 16 years

Sexual Status: Active

Off springs: 1

Sexual maturity: 14 years

Sexual Status: Active

Number of off springs: 1

3

Ethnicity

White American

White American

4

Variation in Growth and development

Achieved growth and developmental milestones at appropriate age

Achieved growth and developmental milestones at appropriate ages

5

Cause of disorder

Stress

Genetic

6

Questions

Not specified

How heredity expressions define our physical and mental health?

How can we avoid this?

7

Communication

Not specified

Concerned with the genetic facts and figures behind illness

Table 2

Maternal Grandparent Genetic History

No.

History

Maternal Grand Father (59 years, Alive)

Maternal Grand Mother (54 years, Alive)

1

Health History

Illness: Benign hypertensive arteriolar Nephrosclerosis

Surgical History: Null

Childhood illness: Null

Gynecological History: Normal

Health maintenance: Active

Illness: Breast Cancer (5 years ago)

Surgical History: Breast Surgery

Childhood illness: Null

Gynecological History: Normal

Health maintenance: Active

2

Reproductive History

Sexual maturity: 15 years

Disorder; Null

Off springs: 2

Sexual maturity: 14 years

Disorder; Null

Off springs: 2

3

Ethnicity

White American

White American

4

Variation in Growth and development

Achieved growth and developmental milestones at appropriate age

Achieved growth and developmental milestones at appropriate ages

5

Cause of disorder

Thyroid problem

Genetic

6

Questions

Not specified

How can we minimize genetic risk?

7

Communication

Not specified

Concerned with the genetic facts and figures behind physical illness

Generation II

Table 3

Parental Genetic History

No.

History

Father (28 years, alive)

Mother (26 years, alive)

1

Health History

Illness: null

Gynecological History: Normal

Health maintenance: Active

Illness: retinoblastoma at 3 yrs

Treatment: Chemotherapy

Gynecological History: Normal birth

Health maintenance: Active

2

Reproductive History

Sexual maturity: 16 years

Sexual Status: Active

Off springs: 3

Sexual maturity: 15 years

Sexual Status: Active

Number of off springs: 3

3

Ethnicity

White American

White American

4

Variation in Growth and development

Achieved growth and developmental milestones at appropriate age

Achieved growth and developmental milestones at appropriate ages

5

Cause of disorder

None

Physical

6

Questions

Not specified

Not specified

7

Communication

Not specified

Not specified

Generation III

Table 4

Patient and sibling history

No.

History

Sibling A (Male, 7 yr)

Sibling B (Male, 5 yr)

Sibling C (Female, 3yr)

1

Health History

Illness: None

Gynecological History: Normal

Illness: Hypospadias (corrected at birth)

Gynecological History: complicated birth

Illness: cat’s eye” reflex

Gynecological History: Normal birth

2

Reproductive History

-

-

-

3

Ethnicity

White American

White American

White American

4

Variation in Growth and development

Achieved growth and developmental milestones at appropriate age

Achieved growth and developmental milestones at appropriate ages

Achieved growth and developmental milestones at appropriate ages

5

Cause of disorder

None

Premature birth

Genetic (mother)

6

Questions

Not specified

Not specified

Not specified

7

Communication

Not specified

Not specified

Not specified

Nursing Interventions

Nursing intervention will include:

Appropriate referral of the patient

Education and support of patient and her family

Interpretation and explanation of genetic factors before patient and her family

Explanation of potential impact of genetic information on patient and family

Explaining various treatment options for cat’s eye reflex including enucleation of the eye, external beam radiography, branchytherapy, thermotherapy, laser photocoagulation, cryotherapy, systematic chemotherapy, intra-arterial chemotherapy, nano-particulate chemotherapy and chemoreduction with their potential side effects (Qaddoumi et. al., 2012; McEvoy et. al., 2014; Tse et. al., 2014; Langenau, 2015).

References

Langenau, D. M., et al. (2015). Preclinical Models Provide Scientific Justification and Translational Relevance for Moving Novel Therapeutics into Clinical Trials for Pediatric Cancer. Cancer Res., 75, 5176–5186.  Retrieved February 21, 2019 from https://www.ncbi.nlm.nih.gov/pubmed/26627009

McEvoy, J., et al. (2014). RB1 gene inactivation by chromothripsis in human retinoblastoma. Oncotarget.  5, 438–450. Retrieved February 21, 2019 from https://www.ncbi.nlm.nih.gov/pubmed/24509483

Qaddoumi, I., et al. (2012). Topotecan and vincristine combination is effective against advanced bilateral intraocular retinoblastoma and has manageable toxicity. Cancer, 118, 5663–5670. Retrieved February 21, 2019 from https://www.ncbi.nlm.nih.gov/pubmed/22516936

Tse B. C., et al. (2013). Superselective intraophthalmic artery chemotherapy in a nonhuman primate model: histopathologic findings. JAMA Ophthalmol, 131, 903–911.  Retrieved February 21, 2019 from https://www.ncbi.nlm.nih.gov/pubmed/23619956